
Case 01 — Crushing pain before breakfast
A 58-year-old man has 45 minutes of crushing retrosternal pain, diaphoresis and nausea. BP 104/68 mmHg.
Open ECG Challenge →Fifty case-based ECG challenges. Read the patient first, inspect the tracing, commit to an interpretation, then reveal the systematic analysis, diagnosis and management.

A 58-year-old man has 45 minutes of crushing retrosternal pain, diaphoresis and nausea. BP 104/68 mmHg.
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A 72-year-old woman has palpitations and exertional breathlessness. Pulse is irregularly irregular at 132/min.
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A 32-year-old man has recurrent nocturnal syncope and a family history of sudden unexplained death.
Open ECG Challenge →A 64-year-old asymptomatic man has a pulse of 58/min before surgery; every P wave is followed by QRS but the PR interval is prolonged.
Open ECG Challenge →A 66-year-old man with hypertension has an incidental broad QRS complex. Compare V1 and the lateral leads.
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A 61-year-old man develops severe central chest pain with vomiting and diaphoresis; BP is 92/60 mmHg.
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A 59-year-old man has persistent chest pain; the standard ECG shows horizontal ST depression across V1–V3 with prominent anterior R waves.
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A 63-year-old man with inferior ST elevation becomes hypotensive; lungs are clear and JVP is elevated.
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A 67-year-old woman has recurrent rest chest pain; serial ECGs show new horizontal ST depression in V4–V6 that improves when pain settles.
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A 54-year-old man had repeated chest pain overnight but is pain-free now; V2–V4 show deeply inverted symmetric T waves.
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A 48-year-old man has ongoing crushing chest pain; precordial leads show upsloping ST depression at the J point with tall symmetric T waves.
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A 35-year-old man has pleuritic chest pain relieved by leaning forward after a viral illness.
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A 70-year-old man with CKD presents with weakness; potassium is 7.2 mmol/L and the ECG shows peaked T waves with QRS widening.
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A 46-year-old woman has vomiting, weakness and palpitations; potassium is 2.5 mmol/L.
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A 42-year-old woman faints after starting a QT-prolonging drug; the corrected QT interval is markedly prolonged.
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A 56-year-old woman develops recurrent syncope with runs of polymorphic wide-complex tachycardia after QT prolongation.
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A 68-year-old man with prior MI has palpitations and BP 86/54 mmHg; ECG shows a regular broad-complex tachycardia.
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A 50-year-old man becomes dizzy with a rapid irregular broad-complex rhythm whose QRS morphology changes beat to beat.
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A 29-year-old woman has abrupt-onset palpitations at 190/min; ECG shows a regular narrow-complex tachycardia with no obvious preceding P waves.
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A 24-year-old man with known pre-excitation develops a regular narrow-complex tachycardia at 210/min.
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A 22-year-old man has episodic palpitations; resting ECG shows a short PR and slurred initial QRS upstroke.
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A 65-year-old man has persistent palpitations at 150/min; the rhythm appears regular until the baseline is examined carefully.
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A 28-year-old asymptomatic athlete has a resting pulse of 44/min and normal blood pressure.
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A 74-year-old woman reports fatigue, presyncope and alternating slow pulse with bursts of atrial tachyarrhythmia.
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A 61-year-old man on an AV-nodal blocker has grouped beating on telemetry.
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A 70-year-old man with syncope has constant PR intervals but intermittent non-conducted P waves.
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A 76-year-old man presents with syncope, HR 32/min and hypotension.
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A 69-year-old man with cardiomyopathy has a broad QRS with a dominant S in V1 and broad notched R waves laterally.
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A 67-year-old man has marked left-axis deviation without LVH or inferior infarction.
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A 73-year-old man has unexplained syncope; ECG shows RBBB plus marked left-axis deviation.
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A 62-year-old man with long-standing hypertension has high QRS voltages and lateral repolarization abnormalities.
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A 55-year-old man with chronic pulmonary hypertension has right-axis deviation and a dominant R wave in V1.
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A 49-year-old woman develops acute pleuritic chest pain, tachycardia and hypoxaemia after prolonged immobilisation.
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A 78-year-old man taking digoxin has no acute symptoms but an ECG with characteristic downsloping ST depression.
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An elderly patient on digoxin with AKI develops nausea, confusion and frequent ectopy.
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An 82-year-old man is found outdoors confused with a core temperature of 30°C.
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A 64-year-old patient with metastatic cancer has calcium 14.2 mg/dL and a shortened QT interval.
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A 45-year-old woman develops perioral tingling after thyroid surgery; calcium is low and QT is prolonged.
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A 25-year-old asymptomatic man has stable concave precordial ST elevation on repeated ECGs.
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A 63-year-old woman develops chest pain after severe emotional stress; ECG shows widespread anterior ST-T abnormalities.
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A 21-year-old athlete has exertional syncope and a harsh systolic murmur.
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A 34-year-old man has palpitations and syncope; ECG shows right-precordial T-wave inversion and ventricular ectopy.
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A 76-year-old man with a pacemaker has regular pacing spikes followed by broad QRS complexes.
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A pacemaker-dependent patient becomes dizzy; pacing spikes are seen but some are not followed by QRS complexes.
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A 58-year-old man notices palpitations; ECG shows a premature broad complex after every sinus beat.
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A 71-year-old man with COPD exacerbation has an irregular narrow-complex tachycardia at 135/min.
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A 69-year-old man after inferior MI has a regular narrow-complex rhythm at 45/min with absent/retrograde P waves.
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A 40-year-old man with pneumonia has HR 128/min; each QRS is preceded by a normal P wave.
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A 56-year-old patient with malignancy has dyspnoea, raised JVP and hypotension; ECG shows beat-to-beat variation in QRS amplitude.
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A 27-year-old man develops chest pain and palpitations one week after a viral syndrome; troponin is elevated.
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